Monitoring Oxidation Reactions by Photochemical Techniques
- This doctoral thesis is devoted to monitor oxidation reactions processes by photochemical techniques. Oxidation reactions play a crucial role in both environmental and biological systems. Therefore, my thesis started with the study of aryl–substituted benzyl radicals. In the second part of my thesis, the effect of the solvent on H atom abstractions from C–H donors by oxygen–centered radicals.
In the last part, I developed a fluorescence–based supramolecular tandem assay to monitor a biologically important oxidation process, namely an enzymatic oxidation. When searching for a macrocyclic receptor (required for tandem assays) for the substrate of peroxidases, namely iodide, I found a novel interaction (halogen bonding) in supramolecular host-guest complexes associated with cucurbiturils, which is based on the encapsulation of molecular iodine inside the nanocavity of CB6.
